Wing Sergeal Petersen will make his Stormers debut in the Super Rugby encounter against the Lions at Newlands.
Petersen starts on the right wing in one of four changes to the Stormers starting line-up for the South African derby, which kicks off at 17:15 on Saturday.
The other changes to the backline see Jean-Luc du Plessis start at flyhalf, with Damian Willemse shifting to fullback in the place on the injured Dillyn Leyds and Joshua Stander coming in on the bench.
The only change to the forward pack is in the second row, with Chris van Zyl at lock in place of the injured Salmaan Moerat.
Fit-again Springboks Frans Malherbe and Eben Etzebeth are among the replacements, along with flank Jaco Coetzee who is also set to get his first run of the campaign.
Stormers head coach Robbie Fleck said that his team is looking forward to playing in front of the Newlands faithful.
"It is always special to play at Newlands in front of our passionate fans, so we will be giving it everything we have got on Saturday.
"We are determined to raise our standards and deliver the type of rugby that we can be proud of," he said.
Teams:
Stormers
15 Damian Willemse, 14 Sergeal Petersen, 13 Ruhan Nel, 12 Damian de Allende, 11 SP Marais, 10 Jean-Luc du Plessis, 9 Jano Vermaak, 8 Sikhumbuzo Notshe, 7 Pieter-Steph du Toit, 6 Siya Kolisi (captain), 5 JD Schickerling, 4 Chris van Zyl, 3 Wilco Louw, 2 Bongi Mbonambi, 1 Ali Vermaak
Substitutes16 Scarra Ntubeni, 17 Corne Fourie, 18 Frans Malherbe, 19 Eben Etzebeth, 20 Jaco Coetzee, 21 Herschel Jantjies, 22 Joshua Stander, 23 Dan du Plessis
Lions
15 Andries Coetzee, 14 Courtnall Skosan, 13 Lionel Mapoe, 12 Harold Vorster, 11 Ruan Combrinck, 10 Elton Jantjies 9 Nic Groom, 8 Warren Whiteley (captain), 7 Kwagga Smith, 6 Marnus Schoeman, 5 Stephan Lewies, 4 Marvin Orie, 3 Carlu Sadie, 2 Malcolm Marx, 1 Dylan Smith
Substitutes: 16 Pieter Jansen, 17 Jacobie Adriaanse, 18 Sti Sithole,19 Rhyno Herbst, 20 Hacjivah Dayimane, 21 Gianni Lombard, 22 Aphiwe Dyantyi, 23 Sylvian Mahuza